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Triclabendazole

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Description | Uses & Side Effects | Warnings

There is currently no information to display in this section. RateADrug provides information about drugs and supplements though a wiki format provided by researchers, health care providers and others. We encourage you to add to this description by clicking on the button below.

Common Uses:

It is used in veterinary practice for the treatment of fascioliasis. Fascioliasis is a condition of herbivorous animals like sheep, cattle, and goats, which are the normal hosts. Humans are accidental hosts. This condition occurs due to consumption of uncooked, and usually unwashed, aquatic vegetables containing parasitic larvae.

Off Label Uses:

Triclabendazole is used as an alternative form of treatment for paragonimiasis caused by Paragonimus westermani (lung fluke).

Side Effects:
Not for use in humans hence side effects in humans are unknown.

Cautions / Warnings:

Usage during pregnancy: Since it is not used in humans no studies have been conducted; however, studies in animals have not shown that triclabendazole causes adverse effects in the fetus.
Usage during breast feeding: Triclabendazole is distributed into breast milk. However it has not been used on humans hence results are unknown.

Drug Interactions:
Not for use in humans hence drug interactions in humans are unknown.

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About Triclabendazole

The commonly used brand name of this medication is Fasinex. It is not commercially available in the U.S. and Canada. It functions as an anthelmintic (systemic) medication. It is used in veterinary practice for the treatment of fascioliasis. Fascioliasis is a condition of herbivorous animals like sheep, cattle, and goats, which are the normal hosts. Humans are accidental hosts. This condition occurs due to consumption of uncooked, and usually unwashed, aquatic vegetables containing parasitic larvae.

About Triclabendazole

Triclabendazole (commercial name Fasinex) is a member of the Benzimidazole family of anthelmintics. The benzimidazole drugs share a common molecular structure, triclabendazole being the exception in having a chlorinated benzene ring but no carbamate group.

Triclabendazole displays high efficacy against both immature and adult liver fluke.

It is generally accepted that benzimidazoles like triclabendazole bind to beta-tubulin and prevent the polymerisation of the microtubules of which they are part.

Source: Wikipedia

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