Pau d’arco was traditionally prized by the major South American civilizations, including the Incas, the Callawaya people in Brazil, and many other Native South American peoples - the lapacho was used extensively as a cure-all by all of these cultures. A large variety of disorders and conditions such as serious and superficial wounds, conditions such as fever, disorders such as dysentery, inflammation in the intestinal region, certain types of cancer, and problems such as snakebites and insect bites were treated using herbal remedies prepared from the lapacho. The lapacho contains a lot of chemical ingredients and active principles, for this reason it is not surprising that the beneficial effects of this herb are still taken advantage of extensively in South America as well as by the majority of herbal practitioners around the world in different countries. Its important roles in herbal medicine include its main action as a natural antibiotic herb for the treatment of all types of bacterial and viral infections which affect the human body, especially when such infections affect parts of the body like the nose, the mouth, and the throat. The herbal remedy is also believed to be very helpful in the treatment of chronic conditions such as ME in affected individuals. Fungal infections of all kinds arising in the body are also normally treated using the lapacho, including common ones like the ringworm and different yeast infections, the herbal remedy is also considered especially effectively and useful for the overall treatment of chronic fungal conditions of all kinds, including the condition known as candidiasis in different people. The reduction and relief of inflammatory conditions on the body is another major beneficial effect of the lapacho, and this action is particularly useful in the treatment of inflammation in the stomach and the intestines. A wide range of inflammatory conditions are treated using the herbal lapacho, these include the treatment of disorders such as cystitis, the treatment of inflammation in the cervix, and in the treatment of disorders such as prostatitis. The treatment of cancer, including leukemia is another area of remedial action in which the lapacho is effective. The combination of traditional knowledge about cancer treatment using lapacho and the clinical experience in Brazil with this compound, requires that the lapacho must be more researched for dormant therapeutic values and further effects for the treatment of this devastating disease.