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TriCor
Fenofibrate
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5.7
Effectiveness
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Holistic Benefits
RateADrug users have reported 2 TriCor side effects and 1 TriCor benefit.
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Description
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There is currently no information to display in this section. RateADrug provides information about drugs and supplements though a wiki format provided by researchers, health care providers and others. We encourage you to add to this description by clicking on the button below.
Common Uses:
Common uses for Tricor include decreasing cholesterol levels in people with high cholesterol and triglyceride levels in people with high triglycerides. TriCor functions by reducing different kinds of cholesterol and increasing the breakdown and removal of triglycerides so that their number in the body is decreased. Tricor is administered along with lifestyle changes such as limited alcohol use, weight loss, exercise, and a diet low in cholesterol and saturated fats.
Off Label Uses:
Currently, there are no known off-label uses for Tricor.
Side Effects:
Some of the common side effects of Tricor include the following:
Chest congestion or difficulty breathing
Abdominal pain (or stomach pain)
Back pain
Headache
Runny nose
Diarrhea or constipation
Nausea
Body weakness
Flu-like symptoms
Tricor could also be responsible for increasing liver enzymes.
Other known side effects of Tricor include:
Unexplained muscle pain, tenderness, or weakness (especially if you have a fever or feel ill)
Nausea or vomiting
Abdominal pain (or stomach pain)
Fever
Passing brown or dark-colored urine
Yellowing of the skin or the whites of the eyes
Feeling more tired that usual
Itching
Unexplained bleeding
Bleeding that seems to take longer to stop
Unexplained rash.
Some uncommon but occasionally occuring side effects of TriCor include:
Chest pain
Serious allergic reactions
High blood pressure (hypertension)
Infections
Increased sun sensitivity
A decrease in certain cells involved with the immune system
Peripheral edema (swelling of the hands and/or feet)
Joint pain (see Tricor and Joint Pain)
Muscle pain
Migraines
Dizziness
Insomnia
Depression (see Tricor and Depression)
A decrease in sexual desire (libido)
Increased appetite
Diabetes
Anemia
Weight gain (see Tricor and Weight Gain)
Anxiety
Dry mouth
Pancreatitis (inflammation of the pancreas)
Skin rash or irritation
Cautions / Warnings:
Prior to commencing TriCor it is advisable to inform and/or consult your physician if you have the following conditions:
Diabetes
Gallbladder disease or gallstones
Cardiac conditions
Kidney disease or kidney failure
Liver disease or liver failure
Thyroid gland problems
An allergy to Tricor or any other medications, foods, dyes, or preservatives.
It is also important to let ones' physician know if one:
Drink alcohol frequently
Are pregnant or planning on becoming pregnant
Are breastfeeding.
It is also advisable to consult or seek advise from ones' physician if one is taking prescription and non-prescription medicines, vitamins, and herbal supplements.
Drug Interactions:
Tricor or fenofibrate could interact with various other medications. Some of the Tricor drug interactions include:
Warfarin
HMG-CoA reductase inhibitors (statins), including:
o Atorvastatin (Lipitor)
o Fluvastatin (Lescol)
o Lovastatin (Mevacor, Altoprev, Advicor)
o Pravastatin (Pravachol)
o Simvastatin (Zocor, Vytorin)
o Rosuvastatin (Crestor)
Cyclosporine (Gengraf, Neoral, Sandimmune)
Bile acid sequestrants (resins), including:
o Cholestyramine (Prevalite, Questran, Questran Light, LoCholest)
o Colestipol (Colestid)
o Colesevelam (WelChol).
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Try adding more purple to your diet!
Purple foods such as concord grapes, blueberries, plums, pomegranates, acai berries, red wine, and even eggplants are very high in antioxidants. Purple foods have been shown to protect your heart and vision, promote mental focus, and increase longevity. Research has indicated that purple foods may even be used to prevent or cure cancer.
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TriCor Comments
27 Mar 2013
Took this drug about 12 yrs ago. At first, it was great, lowered lipids and I was euphoric. It was like an amphetamine without losing sleep. Then I had stomach pains and started defecating what could pass as fresh asphalt. Black and very abrasive. This caused rectal bleeding so I stopped taking it despite the pleas of my doctor. Turns out, all I had to do was limit my consumption of carbs, especially sugar and grains. Doctor never mentioned this. Guess there was no money in it for him. I'm not seeing that doctor any more.
—Posted by Anonymous
29 Nov 2010
I have upon the recomendation of my doctor I have quit taking this medicine
—Posted by nolanco
09 Aug 2010
I've been on this medication for a long time and I have nothing to report.
—Posted by Anonymous
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About TriCor
Tricor (fenofibrate) is a medication that has been licensed to treat several conditions. Tricor uses include the reduction of: Cholesterol levels in patients with hypercholesterolemia (high cholesterol). Tricor can reduce both total and LDL cholesterol (bad cholesterol) and raise HDL cholesterol (good cholesterol). Triglyceride levels in patients with hypertriglyceridemia (high triglycerides). Triglycerides are fat-like substances found in the body. TriCor contains the active ingredient fenofibrate and is available in tablet form. It is a lipid controling agent. Each tablet contains 40 mg or 120 mg fenofibrate. The inactive ingredients of TriCor contain lactose monohydrate, NF; Polyethylene Glycol 6000, NF; Poloxamer 188, NF; and magnesium stearate, NF. TriCor or fenofibrate is indicated as adjunctive therapy to diet to decrease increased LDL-C, Total-C, Triglycerides, and Apo B, and to increase HDL-C in adult patients with primary hyperlipidemia or mixed dyslipidemia. Lipid-altering medicaion should always be administered in conjunction with strict dietary protocol in saturated fat and cholesterol when the response to diet and non-pharmacological interventions is not working sufficiently.
About Fenofibrate
Fenofibrate is a drug of the fibrate class. It is mainly used to reduce cholesterol levels in patients at risk of cardiovascular disease. Like other fibrates it reduces both low-density lipoprotein (LDL) and very low density lipoprotein (VLDL) levels, as well as increasing high-density liporotein (HDL) levels. It also appears to have a beneficial effect on the insulin resistance featured by the metabolic syndrome. It is used alone or in conjunction with statins in the treatment of hypercholesterolemia and hypertriglyceridemia. Fenofibrate is sold under the brand name Triglide by Sciele Pharma and Antara by Oscient Pharmaceuticals.
The pharmaceutical form and the strength may change from one country from another, and from one brand to another. In the United States, Ttricor was reformulated in 2005 and is available in tablets of 45 and 145 mg. This reformulation is controversial and is the subject of antitrust litigation by generic drug manufacturer Teva. In Europe, it is available in coated tablet but also in capsule, the strength range include 67, 145, 160 and 200 mg. The differences in strength belong is due to altered bioavailability (the fraction absorbed by the body) due to particle size. For example: 200 mg can be replaced by 160 mg because its fenofibrate is micronised. The 145 mg strength is a new strength appeared in 2005-2006 which also replaces 200 or 160 mg as the fenofibrate is nanonised (ie the particle size is below 400 nm). Antara is sold in the U.S. as capsules of 43 and 130 mg.
Like the other fibrates, fenofibrate acts on PPAR\u03B1 to reduce cholesterol levels.
A large study in 2005 of fenofibrate in patients with diabetes showed no change in total mortality or coronary artery events, but did show a significant change in overall cardiovascular events, as well as improving some microvascular complications of diabetes.
Like most fibrates, fenofibrate can cause stomach upsets and myopathy (muscle pain) and very rarely rhabdomyolysis. This risk is increased when used together with statins. However, the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study provides important information that long-term treatment with fenofibrate therapy appears to have a favorable safety profile in patients with type 2 diabetes, even when nonstudy lipid-lowering medications were added. In FIELD, there were no cases of rhabdomyolysis reported in patients on combination therapy with fenofibrate and a statin. Thus, there is an increasing body of evidence that fenofibrate/statin combination therapy is safe and effective at managing dyslipidemia in patients with type 2 diabetes who are at risk for cardiovascular events.
Source: Wikipedia
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